| Product Name | Bovine Synaptogyrin-2 (SYNGR2) ELISA Kit |
|---|---|
| Description | Bovine Synaptogyrin-2 (SYNGR2) ELISA Kit has high sensitivity and excellent specificity for detection of Bovine SYNGR2. No significant cross-reactivity or interference between Bovine SYNGR2 and analogues was observed. SYNGR2 encodes an integral membrane protein containing four transmembrane regions and a C-terminal cytoplasmic tail that is tyrosine phosphorylated. The exact function of this protein is unclear, but studies of a similar rat protein suggest that it may play a role in regulating membrane traffic in non-neuronal cells. The gene belongs to the synaptogyrin gene family.Subcellular fractionation of rat brain cells indicated that both synaptogyrin and cellugyrin are associated with microsomes; however, only synaptogyrin is found in synaptic vesicles. The authors suggested that synaptogyrin is a specialized version of the ubiquitous cellugyrin, supporting the concept that synaptic vesicles are a simplified and specialized form of a generic trafficking organelle. This Bovine Synaptogyrin-2 (SYNGR2) ELISA Kit employs a two-site sandwich ELISA to quantitate SYNGR2 in samples. An antibody specific for SYNGR2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySYNGR2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SYNGR2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SYNGR2 bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | SYNGR2, MGC102914, cellugyrin |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Bovine |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 513812 |
| Storage | 2-8°C |
| Background |
SYNGR2 encodes an integral membrane protein containing four transmembrane regions and a C-terminal cytoplasmic tail that is tyrosine phosphorylated. The exact function of this protein is unclear, but studies of a similar rat protein suggest that it may play a role in regulating membrane traffic in non-neuronal cells. The gene belongs to the synaptogyrin gene family.Subcellular fractionation of rat brain cells indicated that both synaptogyrin and cellugyrin are associated with microsomes; however, only synaptogyrin is found in synaptic vesicles. The authors suggested that synaptogyrin is a specialized version of the ubiquitous cellugyrin, supporting the concept that synaptic vesicles are a simplified and specialized form of a generic trafficking organelle. |
| Supplier | Abbkine |
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