| Product Name | Human A Disintegrin And Metalloprotease 19 (ADAM19) ELISA Kit |
|---|---|
| Description | Human A Disintegrin And Metalloprotease 19 (ADAM19) ELISA Kit has high sensitivity and excellent specificity for detection of Human ADAM19. No significant cross-reactivity or interference between Human ADAM19 and analogues was observed. ADAM19 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis.This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Alternative splicing results in two transcript variants. This Human A Disintegrin And Metalloprotease 19 (ADAM19) ELISA Kit employs a two-site sandwich ELISA to quantitate ADAM19 in samples. An antibody specific for ADAM19 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyADAM19 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ADAM19 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ADAM19 bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | ADAM19, FKSG34, MADDAM, MLTNB, ADAM metallopeptidase domain 19, a disintegrin and metalloproteinase domain 19 (meltrin beta), meltrin beta |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Human |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 8728 |
| Storage | 2-8°C |
| Background | ADAM19 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis.This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Alternative splicing results in two transcript variants. |
| Supplier | Abbkine |
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