| Product Name | Human Anti-Mullerian hormone (AMH) ELISA Kit |
|---|---|
| Description | Anti-MÙllerian hormone (AMH) is a dimeric glycoprotein that inhibits the development of the MÙllerian ducts in a male embryo. It is named after Johannes Peter MÙller. AMH is a protein hormone structurally related to inhibin and activin, and a member of the transforming growth factor-_ (TGF-_) family. It is present in fish, reptiles, birds, marsupials, and placental mammals.In mammals AMH is secreted by Sertoli cells of the testes during embryogenesis of the fetal male and prevents the development of the mullerian ducts into the uterus and other mullerian structures. The effect is ipsilateral, that is each testis suppresses MÙllerian development only on its own side. In humans this action takes place by 8 weeks gestation. In female embryogenesis the absence of AMH allows for the development of upper vagina, uterus and cervix, and oviducts. This assay has high sensitivity and excellent specificity for detection of Human AMH. No significant cross-reactivity or interference between Human AMH and analogues was observed. |
| Synonyms | MIF, MIS, Mullerian inhibiting factor|Mullerian inhibiting substance |
| Method | Sandwich ELISA |
| Detection Range | 37.0-3000 pg/mL |
| Sensitivity | 16.3 pg/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | Anti-MÙllerian hormone (AMH) is a dimeric glycoprotein that inhibits the development of the MÙllerian ducts in a male embryo. It is named after Johannes Peter MÙller. AMH is a protein hormone structurally related to inhibin and activin, and a member of the transforming growth factor-_ (TGF-_) family. It is present in fish, reptiles, birds, marsupials, and placental mammals.In mammals AMH is secreted by Sertoli cells of the testes during embryogenesis of the fetal male and prevents the development of the mullerian ducts into the uterus and other mullerian structures. The effect is ipsilateral, that is each testis suppresses MÙllerian development only on its own side. In humans this action takes place by 8 weeks gestation. In female embryogenesis the absence of AMH allows for the development of upper vagina, uterus and cervix, and oviducts. |
| Supplier | Abebio |
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