| Product Name | Human Apolipoprotein C-I (APOC1) ELISA Kit |
|---|---|
| Description | Apolipoprotein C1 is a lipoprotein with a length of 57 amino acids normally found in plasma and responsible for the activation of esterified lechitin cholesterol with an important role in the exchange of esterified cholesterol between lipoproteins and in removal of cholesterol from tissues.Its main function is inhibition of CETP, probably by altering the electric charge of HDL molecules. during fasting (like other apolipoprotein C) is found primarily within HDL, meanwhile after a meal it is found within the surface of other lipoproteins. in contrast when proteins rich in triglycerides like chylomicrons and VLDL are broken down this apoprotein is transferred again to the HDL. Human Apolipoprotein C-I (APOC1) ELISA Kit employs a two-site sandwich ELISA to quantitate APOC1 in samples. An antibody specific for APOC1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any APOC1 present is bound by the immobilized antibody. After removing any unbound substances, HRP-Conjugate Human APOC1 detection antibody is added to the wells. Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of APOC1 bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | APOC1 |
| Method | Sandwich ELISA |
| Detection Range | 11.25 μg/mL-180 μg/mL |
| Sensitivity | 1.0 μg/mL |
| Reactivity | Human |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Storage | 2-8°C |
| Background | Apolipoprotein C1 is a lipoprotein with a length of 57 amino acids normally found in plasma and responsible for the activation of esterified lechitin cholesterol with an important role in the exchange of esterified cholesterol between lipoproteins and in removal of cholesterol from tissues.Its main function is inhibition of CETP, probably by altering the electric charge of HDL molecules. during fasting (like other apolipoprotein C) is found primarily within HDL, meanwhile after a meal it is found within the surface of other lipoproteins. in contrast when proteins rich in triglycerides like chylomicrons and VLDL are broken down this apoprotein is transferred again to the HDL. |
| Supplier | Abbkine |
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