| Product Name | Human Beta-defensin 118 (DEFB118) ELISA Kit |
|---|---|
| Description | Human Beta-defensin 118 (DEFB118) ELISA Kit has high sensitivity and excellent specificity for detection of Human DEFB118. No significant cross-reactivity or interference between Human DEFB118 and analogues was observed. DEFB118 encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of DEFB118 is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity against E. coli. DEFB118 is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. This Human Beta-defensin 118 (DEFB118) ELISA Kit employs a two-site sandwich ELISA to quantitate DEFB118 in samples. An antibody specific for DEFB118 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyDEFB118 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for DEFB118 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of DEFB118 bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | DEFB118, C20orf63, DEFB-18, ESC42, dJ1018D12.3, beta-defensin 118, defensin, beta 18, epididymus specific clone 42 |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Human |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 117285 |
| Storage | 2-8°C |
| Background | DEFB118 encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of DEFB118 is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity against E. coli. DEFB118 is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. |
| Supplier | Abbkine |
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