| Product Name | Human C-X-C chemokine receptor type 2 (IL8RB) ELISA Kit |
|---|---|
| Description | Human C-X-C chemokine receptor type 2 (IL8RB) ELISA Kit has high sensitivity and excellent specificity for detection of Human IL8RB. No significant cross-reactivity or interference between Human IL8RB and analogues was observed. Interleukin 8 receptor, beta is a chemokine receptor. IL8RB is also known as CXCR2, and CXCR2 is now the IUPHAR Committee on Receptor Nomenclature and Drug classification-recommended name.The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. In addition, it binds ligands CXCL2, CXCL3, and CXCL5. This Human C-X-C chemokine receptor type 2 (IL8RB) ELISA Kit employs a two-site sandwich ELISA to quantitate IL8RB in samples. An antibody specific for IL8RB has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyIL8RB present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL8RB is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL8RB bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | IL8RB, CD182, CDw128b, CMKAR2, IL8R2, IL8RA, IL8RB, CXCR2 gene for IL8 receptor type B, GRO/MGSA receptor, chemokine (CXC) receptor 2, high affinity interleukin-8 receptor B, interleukin 8 receptor B, interleuk |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Human |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 3579 |
| Storage | 2-8°C |
| Background |
Interleukin 8 receptor, beta is a chemokine receptor. IL8RB is also known as CXCR2, and CXCR2 is now the IUPHAR Committee on Receptor Nomenclature and Drug classification-recommended name.The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. In addition, it binds ligands CXCL2, CXCL3, and CXCL5. |
| Supplier | Abbkine |
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