| Product Name | Human Disks large-associated protein 2 (DLGAP2) ELISA Kit |
|---|---|
| Description | The product of this gene is one of the membrane-associated guanylate kinases localized at postsynaptic density in neuronal cells. These kinases are a family of signaling molecules expressed at various submembrane domains and contain the PDZ, SH3 and the guanylate kinase domains. This protein may play a role in the molecular organization of synapses and in neuronal cell signaling. Alternatively spliced transcript variants encoding different isoforms have been identified, but their full-length nature is not known.Sequence analysis predicted that the 538-amino acid DLGAP2 shares 52% sequence similarity with DLGAP1 and contains four 14-amino acid repeats and 3 proline-rich regions. Binding analysis showed that DLGAP2, like DLGAP1, interacts with DLG4 and DLG1. This assay has high sensitivity and excellent specificity for detection of Human DLGAP2. No significant cross-reactivity or interference between Human DLGAP2 and analogues was observed. |
| Synonyms | DAP2, SAPAP2, PSD-95/SAP90-binding protein 2|SAP90/PSD-95-associated protein 2|discs large-associated protein 2 |
| Method | Sandwich ELISA |
| Detection Range | Request Information |
| Sensitivity | Request Information |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | The product of this gene is one of the membrane-associated guanylate kinases localized at postsynaptic density in neuronal cells. These kinases are a family of signaling molecules expressed at various submembrane domains and contain the PDZ, SH3 and the guanylate kinase domains. This protein may play a role in the molecular organization of synapses and in neuronal cell signaling. Alternatively spliced transcript variants encoding different isoforms have been identified, but their full-length nature is not known.Sequence analysis predicted that the 538-amino acid DLGAP2 shares 52% sequence similarity with DLGAP1 and contains four 14-amino acid repeats and 3 proline-rich regions. Binding analysis showed that DLGAP2, like DLGAP1, interacts with DLG4 and DLG1. |
| Supplier | Abebio |
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