Human Disrupted in renal carcinoma protein 2 (DIRC2) ELISA Kit
| Product Name | Human Disrupted in renal carcinoma protein 2 (DIRC2) ELISA Kit |
|---|---|
| Description | DIRC2 has a conserved motif that is shared with the major facilitator superfamily of transporters between membrane-spanning domains 2 and 3, and a proline-rich region between membrane-spanning domains 6 and 7. DIRC2 also contains a putative N-glycosylation site and several putative phosphorylation sites. Computer predictions of the putative DIRC2 protein showed significant homology to different members of the major facilitator superfamily of transporters. DIRC2 shares 43% similarity with the human homolog of feline leukemia virus type C receptor (FLVXR), which has been classified as a major facilitator superfamily transporter, and more than 85% homology with Dirc2 from monkey, pig, dog, and mouse. Northern blot analysis revealed a 2.2-kb transcript in most tissues tested, including kidney. This assay has high sensitivity and excellent specificity for detection of Human DIRC2. No significant cross-reactivity or interference between Human DIRC2 and analogues was observed. |
| Synonyms | FLJ14784, RCC4, disrupted in renal cancer protein 2|renal cell carcinoma 4 |
| Method | Sandwich ELISA |
| Detection Range | Request Information |
| Sensitivity | Request Information |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | DIRC2 has a conserved motif that is shared with the major facilitator superfamily of transporters between membrane-spanning domains 2 and 3, and a proline-rich region between membrane-spanning domains 6 and 7. DIRC2 also contains a putative N-glycosylation site and several putative phosphorylation sites. Computer predictions of the putative DIRC2 protein showed significant homology to different members of the major facilitator superfamily of transporters. DIRC2 shares 43% similarity with the human homolog of feline leukemia virus type C receptor (FLVXR), which has been classified as a major facilitator superfamily transporter, and more than 85% homology with Dirc2 from monkey, pig, dog, and mouse. Northern blot analysis revealed a 2.2-kb transcript in most tissues tested, including kidney. |
| Supplier | Abebio |
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