Human EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) ELISA Kit
| Product Name | Human EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) ELISA Kit |
|---|---|
| Description | EDIL3 is a glycoprotein that is secreted by endothelial cells and can associate with the endothelial cell surface and the extracellular matrix. EDIL3 is regulated by hypoxia or vascular injury and has been implicated in vascular remodeling during angiogenesis.The predicted 480-amino acid mouse and human proteins, which are 95% identical, contain a signal peptide, 3 epidermal growth factor (EGF)-like repeats, and 2 discoidin I-like repeats. Northern blot analysis revealed expression of a 6.5-kb transcript in highly vascularized mouse embryonic day-15.5 tissue and in mouse and human endothelial cells, but not in other adult tissues. In situ hybridization analysis showed Del1 expression in developing endocardium at 9.5 days postcoitus and in renal artery and hypertrophic chondrocytes at 13.5 days postcoitus. This assay has high sensitivity and excellent specificity for detection of Human EDIL3. No significant cross-reactivity or interference between Human EDIL3 and analogues was observed. |
| Synonyms | DEL1, MGC26287, EGF-like repeats and discoidin I-like domains-containing protein 3|developmental endothelial locus-1 |
| Method | Sandwich ELISA |
| Detection Range | 0.312-20 ng/mL |
| Sensitivity | 0.127 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | EDIL3 is a glycoprotein that is secreted by endothelial cells and can associate with the endothelial cell surface and the extracellular matrix. EDIL3 is regulated by hypoxia or vascular injury and has been implicated in vascular remodeling during angiogenesis.The predicted 480-amino acid mouse and human proteins, which are 95% identical, contain a signal peptide, 3 epidermal growth factor (EGF)-like repeats, and 2 discoidin I-like repeats. Northern blot analysis revealed expression of a 6.5-kb transcript in highly vascularized mouse embryonic day-15.5 tissue and in mouse and human endothelial cells, but not in other adult tissues. In situ hybridization analysis showed Del1 expression in developing endocardium at 9.5 days postcoitus and in renal artery and hypertrophic chondrocytes at 13.5 days postcoitus. |
| Supplier | Abebio |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
