| Product Name | Human Fatty acid-binding protein, heart (FABP3) ELISA Kit |
|---|---|
| Description | Heart fatty acid binding protein (hFABP) is a novel small cytosolic protein that is abundant in the heart. It is highly cardiac-specific, but is also expressed at low concentrations in tissues outside the heart. After myocardial ischemic damage, hFABP can be detected in the blood as early as 1-3 h after onset of chest pain, with peak values reached at 6-8 h and plasma levels returning to normal within 24-30 h. The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This assay has high sensitivity and excellent specificity for detection of Human FABP3. No significant cross-reactivity or interference between Human FABP3 and analogues was observed. |
| Synonyms | FABP11, H-FABP, MDGI, O-FABP, Fatty acid-binding protein 3, muscle|fatty acid binding protein 11|fatty acid binding protein 3|mammary-derived growth inhibitor |
| Method | Sandwich ELISA |
| Detection Range | 0.156-10 ng/mL |
| Sensitivity | 0.078 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
Heart fatty acid binding protein (hFABP) is a novel small cytosolic protein that is abundant in the heart. It is highly cardiac-specific, but is also expressed at low concentrations in tissues outside the heart. After myocardial ischemic damage, hFABP can be detected in the blood as early as 1-3 h after onset of chest pain, with peak values reached at 6-8 h and plasma levels returning to normal within 24-30 h. The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. |
| Supplier | Abebio |
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