| Product Name | Human Fibroleukin (FGL2) ELISA Kit |
|---|---|
| Description | FGL2 is a 439 amino acid secreted protein that is similar to the _- and _-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds.This protein may play a role in physiologic functions at mucosal sites.Fgl2 is a protein that exhibits pleiotropic effects within the body and is an important immune regulator of both innate and adaptive responses. The protein exists as both a type II transmembrane protein found on the surface of macrophages and endothelial cells and can be constitutively secreted by both CD4+ and CD8+ T cells. This assay has high sensitivity and excellent specificity for detection of Human FGL2. No significant cross-reactivity or interference between Human FGL2 and analogues was observed. |
| Synonyms | T49, pT49, fibrinogen-like protein 2|fibroleukin |
| Method | Sandwich ELISA |
| Detection Range | 0.47-30 ng/mL |
| Sensitivity | 0.19 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | FGL2 is a 439 amino acid secreted protein that is similar to the _- and _-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds.This protein may play a role in physiologic functions at mucosal sites.Fgl2 is a protein that exhibits pleiotropic effects within the body and is an important immune regulator of both innate and adaptive responses. The protein exists as both a type II transmembrane protein found on the surface of macrophages and endothelial cells and can be constitutively secreted by both CD4+ and CD8+ T cells. |
| Supplier | Abebio |
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