| Product Name | Human Flavin reductase (BLVRB) ELISA Kit |
|---|---|
| Description | The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B. BLVRB is found predominantly in fetal liver. BLVRA is a major component of human adult liver and is identical to the enzyme previously reported as biliverdin reductase.The FLR cDNA, which appeared to be identical to the BLVRB cDNA, encodes a deduced 206-amino acid protein. Western blot analysis of rat tissues showed highest levels of FLR in the erythrocytes and liver. Northern blot analysis detected a 1.1-kb transcript in human tissues. that flavins are the effective electron acceptor of the enzyme and purified FLR to homogeneity. This assay has high sensitivity and excellent specificity for detection of Human BLVRB. No significant cross-reactivity or interference between Human BLVRB and analogues was observed. |
| Synonyms | BVRB, FLR, MGC117413, SDR43U1, flavin reductase (NADPH)|short chain dehydrogenase/reductase family 43U, member 1 |
| Method | Sandwich ELISA |
| Detection Range | 0.312-20 ng/mL |
| Sensitivity | 0.124 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B. BLVRB is found predominantly in fetal liver. BLVRA is a major component of human adult liver and is identical to the enzyme previously reported as biliverdin reductase.The FLR cDNA, which appeared to be identical to the BLVRB cDNA, encodes a deduced 206-amino acid protein. Western blot analysis of rat tissues showed highest levels of FLR in the erythrocytes and liver. Northern blot analysis detected a 1.1-kb transcript in human tissues. that flavins are the effective electron acceptor of the enzyme and purified FLR to homogeneity. |
| Supplier | Abebio |
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