| Product Name | Human Helicase ARIP4 (RAD54L2) ELISA Kit |
|---|---|
| Description | Adrenergic receptors (ARs) include four general types that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins. RAD54L2 (RAD54-like 2), also known as ARIP4, HSPC325 or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. RAD54L2 is posttranslationally sumoylated or phosphorylated upon DNA damage. This assay has high sensitivity and excellent specificity for detection of Human RAD54L2. No significant cross-reactivity or interference between Human RAD54L2 and analogues was observed. |
| Synonyms | FLJ21396, FLJ22400, HSPC325, KIAA0809, SRISNF2L, RAD54-like 2 |
| Method | Sandwich ELISA |
| Detection Range | 0.312-20 ng/mL |
| Sensitivity | 0.115 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
Adrenergic receptors (ARs) include four general types that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins. RAD54L2 (RAD54-like 2), also known as ARIP4, HSPC325 or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. RAD54L2 is posttranslationally sumoylated or phosphorylated upon DNA damage. |
| Supplier | Abebio |
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