Human Lysophosphatidylcholine acyltransferase 1 (LPCAT1) ELISA Kit
| Product Name | Human Lysophosphatidylcholine acyltransferase 1 (LPCAT1) ELISA Kit |
|---|---|
| Description | Lysophosphatidylcholine (LPC) acyltransferase (LPCAT) catalyzes the conversion of LPC to phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis. deduced 534-amino acid mouse and human proteins contain 3 transmembrane domains, several motifs conserved in members of the LPCAT family, a putative EF hand domain, and a C-terminal endoplasmic reticulum (ER) retention signal. They share about 88% amino acid identity. Real-time RT-PCR of mouse tissues showed that Lpcat1 was expressed at highest levels in lung, followed by spleen and brain. Other tissues had low Lpcat1 levels. Confocal microscopy detected epitope-tagged Lpcat1 mainly in the ER and Golgi of transfected cells. This assay has high sensitivity and excellent specificity for detection of Human LPCAT1. No significant cross-reactivity or interference between Human LPCAT1 and analogues was observed. |
| Synonyms | AYTL2, FLJ12443, FLJ41609, PFAAP3, lpcat, LPC acyltransferase|acyl-CoA:lysophosphatidylcholine acyltransferase 1|acyltransferase like 2|phosphonoformate immuno-associated protein 3|regulated by phos |
| Method | Sandwich ELISA |
| Detection Range | 3.12-200 ng/mL |
| Sensitivity | 1.14 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
Lysophosphatidylcholine (LPC) acyltransferase (LPCAT) catalyzes the conversion of LPC to phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis. deduced 534-amino acid mouse and human proteins contain 3 transmembrane domains, several motifs conserved in members of the LPCAT family, a putative EF hand domain, and a C-terminal endoplasmic reticulum (ER) retention signal. They share about 88% amino acid identity. Real-time RT-PCR of mouse tissues showed that Lpcat1 was expressed at highest levels in lung, followed by spleen and brain. Other tissues had low Lpcat1 levels. Confocal microscopy detected epitope-tagged Lpcat1 mainly in the ER and Golgi of transfected cells. |
| Supplier | Abebio |
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