Human Melanin-concentrating hormone receptor 1 (MCHR1) ELISA Kit
| Product Name | Human Melanin-concentrating hormone receptor 1 (MCHR1) ELISA Kit |
|---|---|
| Description | Melanin-concentrating hormone receptor 1 is one of the melanin-concentrating hormone receptors.The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.MCH1 is thought to have a number of functions including in the regulation of appetite, and in stress, anxiety and depression.Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart. This assay has high sensitivity and excellent specificity for detection of Human MCHR1. No significant cross-reactivity or interference between Human MCHR1 and analogues was observed. |
| Synonyms | GPR24, MCH1R, MGC32129, SLC1, G protein-coupled receptor 24|G-protein coupled receptor 24 |
| Method | Sandwich ELISA |
| Detection Range | 0.312-20 ng/mL |
| Sensitivity | 0.109 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | Melanin-concentrating hormone receptor 1 is one of the melanin-concentrating hormone receptors.The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.MCH1 is thought to have a number of functions including in the regulation of appetite, and in stress, anxiety and depression.Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart. |
| Supplier | Abebio |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
