Human Neuronal acetylcholine receptor subunit alpha-3 (CHRNA3) ELISA Kit
| Product Name | Human Neuronal acetylcholine receptor subunit alpha-3 (CHRNA3) ELISA Kit |
|---|---|
| Description | Neuronal acetylcholine receptor subunit alpha-3 is a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues.The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. This assay has high sensitivity and excellent specificity for detection of Human CHRNA3. No significant cross-reactivity or interference between Human CHRNA3 and analogues was observed. |
| Synonyms | LNCR2, MGC104879, NACHRA3, PAOD2, cholinergic receptor, nicotinic, alpha polypeptide 3|neuronal nicotinic acetylcholine receptor, alpha3 subunit |
| Method | Sandwich ELISA |
| Detection Range | 0.312-20 ng/mL |
| Sensitivity | 0.107 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | Neuronal acetylcholine receptor subunit alpha-3 is a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues.The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. |
| Supplier | Abebio |
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