| Product Name | Human Neutral amino acid transporter B (SLC1A5) ELISA Kit |
|---|---|
| Description | A common cell surface receptor is used for cell entry by the RD114/simian type D retroviruses, which include the feline endogenous retrovirus RD114, all strains of simian immunosuppressive type D retroviruses, the avian reticuloendotheliosis group, including spleen necrosis virus, and baboon endogenous virus. SLC1A5 also serves as a retrovirus receptor, and RDR shows specific transport of neutral amino acids. By radiation hybrid mapping, they localized the receptor to a 500-kb region on chromosome 19q13.3. Infection of cells with RD114/type D retroviruses resulted in an impaired amino acid transport, suggesting a mechanism for virus toxicity and immunosuppression. This assay has high sensitivity and excellent specificity for detection of Human SLC1A5. No significant cross-reactivity or interference between Human SLC1A5 and analogues was observed. |
| Synonyms | AAAT, ASCT2, ATBO, FLJ31068, M7V1, M7VS1, R16, RDRC, RD114 virus receptor|baboon M7 virus receptor|neutral amino acid transporter B|solute carrier family 1 member 5 |
| Method | Sandwich ELISA |
| Detection Range | 0.312-20 ng/mL |
| Sensitivity | 0.124 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
A common cell surface receptor is used for cell entry by the RD114/simian type D retroviruses, which include the feline endogenous retrovirus RD114, all strains of simian immunosuppressive type D retroviruses, the avian reticuloendotheliosis group, including spleen necrosis virus, and baboon endogenous virus. SLC1A5 also serves as a retrovirus receptor, and RDR shows specific transport of neutral amino acids. By radiation hybrid mapping, they localized the receptor to a 500-kb region on chromosome 19q13.3. Infection of cells with RD114/type D retroviruses resulted in an impaired amino acid transport, suggesting a mechanism for virus toxicity and immunosuppression. |
| Supplier | Abebio |
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