| Product Name | Human Nidogen (NID) ELISA Kit |
|---|---|
| Description | Entactin (or nidogen) is a component of the basement membrane alongside other components such as collagen type IV, proteoglycans ( heparan sulfate and glycosaminoglycans), laminin and fibronectin. Entactin (or nidogen) is a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes, and may play a role in cell interactions with the extracellular matrix. Entactin, a 150-kD sulfated glycoprotein, is a major component of basement membranes and forms a highly stable noncovalent complex with laminin. Durkin et al. (1988) derived the complete amino acid sequence of mouse entactin from sequencing of cDNA clones. This assay has high sensitivity and excellent specificity for detection of Human NID1. No significant cross-reactivity or interference between Human NID1 and analogues was observed. |
| Synonyms | NID, enactin|entactin |
| Method | Sandwich ELISA |
| Detection Range | 0.78-50 ng/mL |
| Sensitivity | 0.33 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
Entactin (or nidogen) is a component of the basement membrane alongside other components such as collagen type IV, proteoglycans ( heparan sulfate and glycosaminoglycans), laminin and fibronectin. Entactin (or nidogen) is a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes, and may play a role in cell interactions with the extracellular matrix. Entactin, a 150-kD sulfated glycoprotein, is a major component of basement membranes and forms a highly stable noncovalent complex with laminin. Durkin et al. (1988) derived the complete amino acid sequence of mouse entactin from sequencing of cDNA clones. |
| Supplier | Abebio |
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