| Product Name | Human Proline-rich membrane anchor 1 (PRIMA1) ELISA Kit |
|---|---|
| Description | As a tetramer, acetylcholinesterase (AChE) is anchored to the basal lamina of the neuromuscular junction and to the membrane of neuronal synapses. collagen Q (ColQ) anchors AChE at the neuromuscular junction.PRiMA (proline-rich membrane anchor) encoding the AChE anchor in mammalian brain. PRiMA is able to organize AChE into tetramers and to anchor them at the surface of transfected cells. AChE is actually anchored in neural cell membranes through its interaction with PRiMA. PRiMA anchors AChE in mammalian brain and muscle cell membranes. Required to anchor acetylcholinesteras. This assay has high sensitivity and excellent specificity for detection of Human PRIMA1. No significant cross-reactivity or interference between Human PRIMA1 and analogues was observed. |
| Synonyms | PRIMA, OTTHUMP00000180666|acetylcholinesterase membrane anchor precursor PRiMA |
| Method | Sandwich ELISA |
| Detection Range | Request Information |
| Sensitivity | Request Information |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
As a tetramer, acetylcholinesterase (AChE) is anchored to the basal lamina of the neuromuscular junction and to the membrane of neuronal synapses. collagen Q (ColQ) anchors AChE at the neuromuscular junction.PRiMA (proline-rich membrane anchor) encoding the AChE anchor in mammalian brain. PRiMA is able to organize AChE into tetramers and to anchor them at the surface of transfected cells. AChE is actually anchored in neural cell membranes through its interaction with PRiMA. PRiMA anchors AChE in mammalian brain and muscle cell membranes. Required to anchor acetylcholinesteras |
| Supplier | Abebio |
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