Human Receptor II for the Fc region of immunoglobulin G (FcGRII) ELISA Kit
| Product Name | Human Receptor II for the Fc region of immunoglobulin G (FcGRII) ELISA Kit |
|---|---|
| Description | CD32 is a surface receptor protein and part of a large population of B cell co-receptors. It has a low-affinity for IgG antibodies and down-regulates antibody production in the presence of IgG. This feedback loops essentially lowers the production of IgG produced by B cells when there is a surplus in the body.Monoclonal antibodies can distinguish between type A and type B.Receptors for the Fc portion of IgG such as FCGR2A play an essential role in the protection of the organism against foreign antigens by removing antigen-antibody complexes from the circulation. Receptors are present on monocytes, macrophages, neutrophils, natural killer (NK) cells, and T and B lymphocytes, and they participate in diverse functions such as phagocytosis of immune complexes and modulation of antibody production by B cells. This assay has high sensitivity and excellent specificity for detection of Human FcGRII. No significant cross-reactivity or interference between Human FcGRII and analogues was observed. |
| Synonyms | CD32, FCGR2A, FCG2, FCGR2A1, FCGR2, FCGR2B, FCGR2C, Fc Fragment Of IgG, Low Affinity IIa, Receptor |
| Method | Sandwich ELISA |
| Detection Range | 46.88-3000 pg/mL |
| Sensitivity | 17.35 pg/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | CD32 is a surface receptor protein and part of a large population of B cell co-receptors. It has a low-affinity for IgG antibodies and down-regulates antibody production in the presence of IgG. This feedback loops essentially lowers the production of IgG produced by B cells when there is a surplus in the body.Monoclonal antibodies can distinguish between type A and type B.Receptors for the Fc portion of IgG such as FCGR2A play an essential role in the protection of the organism against foreign antigens by removing antigen-antibody complexes from the circulation. Receptors are present on monocytes, macrophages, neutrophils, natural killer (NK) cells, and T and B lymphocytes, and they participate in diverse functions such as phagocytosis of immune complexes and modulation of antibody production by B cells. |
| Supplier | Abebio |
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