Human Receptor-type tyrosine-protein phosphatase F (PTPRF) ELISA Kit
| Product Name | Human Receptor-type tyrosine-protein phosphatase F (PTPRF) ELISA Kit |
|---|---|
| Description | Receptor-type tyrosine-protein phosphatase F is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherens junctions, as well as in the control of beta-catenin signaling. This assay has high sensitivity and excellent specificity for detection of Human PTPRF. No significant cross-reactivity or interference between Human PTPRF and analogues was observed. |
| Synonyms | FLJ43335, FLJ45062, FLJ45567, LAR, LCA-homolog|OTTHUMP00000008683|OTTHUMP00000008684|leukocyte antigen-related (LAR) PTP receptor|leukocyte antigen-related tyrosine phosphatase|protein tyrosine phos |
| Method | Sandwich ELISA |
| Detection Range | 0.781-50 ng/mL |
| Sensitivity | 0.31 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
Receptor-type tyrosine-protein phosphatase F is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherens junctions, as well as in the control of beta-catenin signaling. |
| Supplier | Abebio |
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