Human Receptor-type tyrosine-protein phosphatase gamma (PTPRG) ELISA Kit
| Product Name | Human Receptor-type tyrosine-protein phosphatase gamma (PTPRG) ELISA Kit |
|---|---|
| Description | Receptor-type tyrosine-protein phosphatase gamma is member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. This assay has high sensitivity and excellent specificity for detection of Human PTPRG. No significant cross-reactivity or interference between Human PTPRG and analogues was observed. |
| Synonyms | HPTPG, PTPG, R-PTP-GAMMA, RPTPG, H_RG317H01.1|protein tyrosine phosphatase gamma|protein tyrosine phosphatase, receptor type, gamma polypeptide|receptor type protein tyrosine phosphatase gamma|recep |
| Method | Sandwich ELISA |
| Detection Range | 0.312-20 ng/mL |
| Sensitivity | 0.117 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | Receptor-type tyrosine-protein phosphatase gamma is member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. |
| Supplier | Abebio |
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