| Product Name | Human Retinoic acid receptor gamma (RARG) ELISA Kit |
|---|---|
| Description | Retinoic acid receptors are retinoic acid-inducible enhancer factors belonging to the superfamily of steroid/thyroid nuclear receptors. A third type of receptor, Retinoic Acid Receptor Gamma, was first identified in the mouse where its RNA was detected predominantly in skin, a well-known target for retinoic acid. Krust et al. (1989) used mouse cDNA to clone the human counterpart. Comparisons of the amino acid sequences of all 6 human and mouse RARs indicated that the interspecies conservation of a given member of the RAR subfamily, i.e., alpha, beta, or gamma, is much higher than the conservation of all 3 receptors in a given species. These observations indicate that the 3 forms of retinoic acid receptor may perform specific functions. This assay has high sensitivity and excellent specificity for detection of Human RARG. No significant cross-reactivity or interference between Human RARG and analogues was observed. |
| Synonyms | NR1B3, RARC, |
| Method | Sandwich ELISA |
| Detection Range | 0.156-10 ng/mL |
| Sensitivity | 0.064 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | Retinoic acid receptors are retinoic acid-inducible enhancer factors belonging to the superfamily of steroid/thyroid nuclear receptors. A third type of receptor, Retinoic Acid Receptor Gamma, was first identified in the mouse where its RNA was detected predominantly in skin, a well-known target for retinoic acid. Krust et al. (1989) used mouse cDNA to clone the human counterpart. Comparisons of the amino acid sequences of all 6 human and mouse RARs indicated that the interspecies conservation of a given member of the RAR subfamily, i.e., alpha, beta, or gamma, is much higher than the conservation of all 3 receptors in a given species. These observations indicate that the 3 forms of retinoic acid receptor may perform specific functions. |
| Supplier | Abebio |
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