| Product Name | Human Secretoglobin family 1D member 2 (SCGB1D2) ELISA Kit |
|---|---|
| Description | LIPB is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2.Highest expression was found in skeletal muscle. Expressed as well in thymus, trachea, kidney, steroid responsive tissues and salivary gland. This assay has high sensitivity and excellent specificity for detection of Human SCGB1D2. No significant cross-reactivity or interference between Human SCGB1D2 and analogues was observed. |
| Synonyms | LIPB, LPHB, lipophilin B|lipophilin B (uteroglobin family member), prostatein-like|prostatein-like lipophilin B |
| Method | Sandwich ELISA |
| Detection Range | 0.312-20 ng/mL |
| Sensitivity | 0.112 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | LIPB is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2.Highest expression was found in skeletal muscle. Expressed as well in thymus, trachea, kidney, steroid responsive tissues and salivary gland. |
| Supplier | Abebio |
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