| Product Name | Human SPOC domain-containing protein 1 (SPOCD1) ELISA Kit |
|---|---|
| Description | SPOCD1 Contains 1 SPOC domain. Contains 1 TFIIS central domain.The Split ends (Spen) family are large proteins characterised by N-terminal RNA recognition motifs (RRMs) and a conserved SPOC (Spen paralog and ortholog C-terminal) domain.The widely distributed DIO (Death inducer-obliterator) family is related to cancer and apoptosis and offers new clues about SPOC domain functionality. TFIIS is a transcription elongation factor, which directly binds the transcription motor, RNA Polymerase II and allows it to read through various transcription arrest sites. TFIIS, a transcription elongation factor, and its affect on proliferation of cancer cells in culture. Knockdown of TFIIS reduced cancer cell proliferation in breast, lung and pancreatic cancer cell lines. This assay has high sensitivity and excellent specificity for detection of Human SPOCD1. No significant cross-reactivity or interference between Human SPOCD1 and analogues was observed. |
| Synonyms | FLJ25348, FLJ39908, RP11-84A19.1, |
| Method | Sandwich ELISA |
| Detection Range | 0.156-10 ng/mL |
| Sensitivity | 0.067 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
SPOCD1 Contains 1 SPOC domain. Contains 1 TFIIS central domain.The Split ends (Spen) family are large proteins characterised by N-terminal RNA recognition motifs (RRMs) and a conserved SPOC (Spen paralog and ortholog C-terminal) domain.The widely distributed DIO (Death inducer-obliterator) family is related to cancer and apoptosis and offers new clues about SPOC domain functionality. TFIIS is a transcription elongation factor, which directly binds the transcription motor, RNA Polymerase II and allows it to read through various transcription arrest sites. TFIIS, a transcription elongation factor, and its affect on proliferation of cancer cells in culture. Knockdown of TFIIS reduced cancer cell proliferation in breast, lung and pancreatic cancer cell lines. |
| Supplier | Abebio |
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