Recombinant Zaire ebolavirus Pre-small/secreted glycoprotein (GP)
| Product Name | Recombinant Zaire ebolavirus Pre-small/secreted glycoprotein (GP) |
|---|---|
| Description | sGP seems to possess an anti-inflammatory activity as it can reverse the barrier-decreasing effects of TNF alpha. Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. Does not seem to be involved in activation of primary macrophages. Does not seem to interact specifically with neutrophils Delta-peptide does not seem to be involved in activation of primary macrophages. |
| Synonyms |
Cleaved into the following 2 chains: Small/secreted glycoprotein Short name: sGP Delta-peptide |
| Host | E.coli |
| Molecular Weight | 41.3 |
| Amino Acid Sequence | IPLGVIHNSTLQVNDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKTSLEKFAVKSCLSQLYQTEPKTSVVRVRRELLPTQGPTQQLKTTKSWLQKIPLQWFKCTVKEGKLQCRI |
| Protein Length | Full Length, 33-364aa |
| Tag | N-terminal 6xHis-tagged |
| Reactivity | Virus |
| Applications | SDS-PAGE |
| Form | Liquid, in Tris-based buffer, 50% glycerol |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| References |
"Emergence of subtype Zaire Ebola virus in Gabon."Volchkov V., Volchkova V., Eckel C., Klenk H.-D., Bouloy M., Leguenno B., Feldmann H. Virology 232:139-144(1997) |
| Background |
sGP seems to possess an anti-inflammatory activity as it can reverse the barrier-decreasing effects of TNF alpha. Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. Does not seem to be involved in activation of primary macrophages. Does not seem to interact specifically with neutrophils Delta-peptide does not seem to be involved in activation of primary macrophages. |
| Supplier | Cusabio |
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