| Product Name | TAC1, 20-129aa, Human |
|---|---|
| Description | TAC1, also known as protachykinin 1, is a member of the tachykinin peptide hormone family. TAC1 are a family of peptides that have similar biologic activities and share a common C-terminal sequence, phe-X-gly-leu-met-NH2, but have distinct N-terminal sequences that convey receptor specificities. TAC1 is thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. It is known to induce behavioral responses and function as vasodilators and secretagogues. Recombinant human TAC1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Synonyms | Protachykinin-1, Protachykinin 1, 4930528L02Rik, NK-1, NK1, Nka, Nkna, Neurokinin 2, Neurokinin A, Neurokinin alpha, Neuromedin L, Neuropeptide K, Substance P, Tachykinin precursor 1 |
| Host | E. coli |
| Molecular Weight | 26.7 kDa (241aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMEEIGA NDDLNYWSDW YDSDQIKEEL PEPFEHLLQR IARRPKPQQF FGLMGKRDAD SSIEKQVALL KALYGHGQIS HKRHKTDSFV GLMGKRALNS VAYERSAMQN YERRR |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Advenier C. et al. (1997) Eur Respir J. 10:1892-1906. Bannon MJ. et al. (1992) Brain Res Mol Brain Res. 12:225-231. |
| Background | TAC1, also known as protachykinin 1, is a member of the tachykinin peptide hormone family. TAC1 are a family of peptides that have similar biologic activities and share a common C-terminal sequence, phe-X-gly-leu-met-NH2, but have distinct N-terminal sequences that convey receptor specificities. TAC1 is thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. It is known to induce behavioral responses and function as vasodilators and secretagogues. Recombinant human TAC1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Supplier | ARP |
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