TAGLN3, 1-199aa, Human

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Product Name TAGLN3, 1-199aa, Human
Background TAGLN3, also known as transgelin-3, contains a putative Actin-binding domain, two EF-hand motifs, two potential phosphorylation sites and a calponin-homology (CH) domain. It shares homology with transgelin and calponin, two cytoskeleton-interacting proteins. Belonging to the calponin family, TAGLN3 co-localizes with Actin and tubulin, suggesting a possible role for it in neuronal plasticity or as a signaling protein. Due to a varied expression pattern, it may play different roles in the developing and adult brain. Recombinant human TAGLN3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Species Human
Synonyms Transgelin-3, NP22, NP25
Host E.coli
Tag His-tag
Molecular Weight 67.1 kDa (581aa)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 0.1M NaCl,1mM DTT, 0.1mM PMSF
Concentration 0.5 mg/ml (determined by Bradford assay)
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI NP_037391
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Ren W.Z. et al. (1994) Brain Res.Mol. Brain Res. 22: 173-185.
Fan L. et al. (2001) J. Neurochem. 76: 1275-1281.

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