| Product Name | TBC1D1, 1-265aa, Human |
|---|---|
| Description | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1, also known as TBC1D1, may act as a GTPase-activating protein for Rab family protein(s). This protein may play a role in the cell cycle and differentiation of various tissues. This protein is involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells. Recombinant human TBC1D1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Synonyms | TBC, TBC1 |
| Host | E. coli |
| Molecular Weight | 34.8 kDa (313aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMSEEEAF KMLKFLMFDM GLRKQYRPDM IILQIQMYQL SRLLHDYHRD LYNHLEEHEI GPSLYAAPWF LTMFASQFPL GFVARVFDMI FLQGTEVIFK VALSLLGSHK PLILQHENLE TIVDFIKSTL PNLGLVQMEK TINQVFEMDI AKQLQAYEVE YHVLQEELID SSPLSDNQRM DKLEKTNSSL RKQNLDLLEQ LQVANGRIQS LEATIEKLLS SESKLKQAML TLELERSALL QTVEELRRRS AEPSDREPEC TQPEPTGD |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea |
| Concentration | 0.25mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Stone S., et al. (2006) Hum. Mol. Genet. 15:2709-2720 Meyre D., et al. (2008) Hum. Mol. Genet. 17:1798-1802 |
| Background | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1, also known as TBC1D1, may act as a GTPase-activating protein for Rab family protein(s). This protein may play a role in the cell cycle and differentiation of various tissues. This protein is involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells. Recombinant human TBC1D1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Supplier | ARP |
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