| Product Name | TBC1D22B, 1-505aa, Human |
|---|---|
| Description | TBC1D22B also known as TBC1 domain family member 22B. TBC1D22B may act as a GTPase-activating protein for Rab family protein. The Tre-2/Bub2/Cdc16 (TBC) domain is a conserved protein motif that consists of approximately 200 amino acids and is thought to function as a specific Rab-GAP domain. The TBC domain is more than 40 distinct TBC domain-containing proteins have been identified in humans. Recombinant human TBC1D22B was expressed in E.coli and purified by using conventional chromatography techniques |
| Synonyms | TBC1 domain family member 22B, C6orf197,dJ744I24.2 |
| Host | E. coli |
| Molecular Weight | 27.8kDa (255aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAAENSK QFWKRSAKLP GSIQPVYGAQ HPPLDPRLTK NFIKERSKVN TVPLKNKKAS SFHEFARNTS DAWDIGDDEE EDFSSPSFQT LNSKVALATA AQVLENHSKL RVKPERSQST TSDVPANYKV IKSSSDAQLS RNSSDTCLRN PLHKQQSLPL RPIIPLVARI SDQNASGAPP MTVREKTRLE KFRQLLSSQN TDLDELRKCS WPGVPREVRP ITWRLLSGYL PANTERRKLT LQRKREEYFG FIEQYYDSRN EEHHQDTYRQ IHIDIPRTNP LIPLFQQPLV QEIFERILFI WAIRHPASGY VQGINDLVTP FFVVFLSEYV EEDVENFDVT NLSQDMLRSI EADSFWCMSK LLDGIQDNYT FAQPGIQKKV KALEELVSRI DEQVHNHFRR YEVEYLQFAF RWMNNLLMRE LPLRCTIRLW DTYQSEPEGF SHFHLYVCAA FLIKWRKEIL DEEDFQGLLM LLQNLPTIHW GNEEIGLLLA EAYRLKYMFA DAPNHYRR |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol |
| Concentration | 0.5mg/ml (determined by Bradford assay) |
| Purity | > 80% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Ishibashi K. et al. (2009) Genes Cells 14:41-52. Mayya V. et al. (2009) Sci. Signal. 2:RA46-RA46. |
| Background | TBC1D22B also known as TBC1 domain family member 22B. TBC1D22B may act as a GTPase-activating protein for Rab family protein. The Tre-2/Bub2/Cdc16 (TBC) domain is a conserved protein motif that consists of approximately 200 amino acids and is thought to function as a specific Rab-GAP domain. The TBC domain is more than 40 distinct TBC domain-containing proteins have been identified in humans. Recombinant human TBC1D22B was expressed in E.coli and purified by using conventional chromatography techniques |
| Supplier | ARP |
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