| Product Name | TCHP Antibody, HRP conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against TCHP conjugated to HRP |
| Synonyms | TCHP antibody; Trichoplein keratin filament-binding protein antibody; Protein TCHP antibody; Mitochondrial protein with oncostatic activity antibody; Mitostatin antibody; Tumor suppressor protein antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | HRP |
| Immunogen | Recombinant human Trichoplein keratin filament-binding protein (1-498AA) |
| Isotype | IgG |
| Target | TCHP |
| Reactivity | Human |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q9BT92 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598). |
| Supplier | Cusabio |
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