Product Name | TGFβ2 Rabbit Polyclonal Antibody |
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Description | transforming growth factor beta 2(TGFB2) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the an |
Synonyms | TGFB2; Transforming growth factor beta-2; TGF-beta-2; BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; Polyergin |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | The antiserum was produced against synthesized peptide derived from human TGF beta2. AA range:361-410 |
Isotype | IgG |
Molecular Weight | 44 |
Reactivity | Human, Mouse, Rat |
Applications | ELISA, IHC-P, WB |
Diluent Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Concentration | 1 mg/ml |
Storage | Store at -20°C. Avoid repeated freeze-thaw cycles. |
Supplier | ELK Biotechnology |
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