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|Product Name||Thiosulfate sulfurtransferase, 1-297aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MVHQVLYRAL VSTKWLAESI RTGKLGPGLR VLDASWYSPG TREARKEYLE RHVPGASFFD IEECRDTASP YEMMLPSEAG FAEYVGRLGI SNHTHVVVYD GEHLGSFYAP RVWWMFRVFG HRTVSVLNGG FRNWLKEGHP VTSEPSRPEP AVFKATLDRS LLKTYEQVLE NLESKRFQLV DSRSQGRFLG TEPEPDAVGL DSGHIRGAVN MPFMDFLTED GFEKGPEELR ALFQTKKVDL SQPLIATCRK GVTACHVALA AYLCGKPDVA VYDGSWSEWF RRAPPESRVS QGKSEKA|
|Background||Thiosulfate sulfurtransferase (TST), also known as Rhodanese, is a mitochondrial enzyme that involved in cyanide detoxification and the modification of sulfur-containing enzymes. This protein contains two highly conservative domains, known as rhodanese homology domains. In mammals, most cyanide is converted to thiocyanate by this enzyme. TST also has weak mercaptopyruvate sulfurtransferase activity. Recombinant TST protein was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol|
|Intended Use||For Research Use Only|
|Molecular Weight||18.6 kDa (160aa), confirmed by MALDI-TOF.|
|NCBI Accession #||NP_003303|
|Purity||> 95% by SDS-PAGE|
|References||Pallini R., et al. (1991) Biochem Biophys Res Commun. 180(2):887-93.
Aita N., et al. (1997) Biochem Biophys Res Commun. 231(1):56-60.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||RDS, TST, Rhodanese, Thiosulfate Sulfurtransferase|
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