| Product Name | THY1, 20-130aa, Human, Baculovirus |
|---|---|
| Description | THY1, as known as Thy-1 membrane glycoprotein, is a cell membrane protein which contains 1lg-like V-type (immunoglobulin-like) domain. This protein is a member of the immunoglobulin superfamily of adhesion molecules with constitutive expression on fibroblast cells. It can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Also, this protein led to some of the initial biochemical description and characterization of a vertebrate glycophosphatidylinositol (GPI) anchor and also the first demonstration of tissue specific differential glycosylation. Recombinant human THY1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | Thy-1 membrane glycoprotein, THY1, CD90, CDw90, CD7, CD90 antigen, CDw90, FLJ33325, MGC128895, T25, Theta antigen, Thy 1, Thy 1 cell surface antigen, Thy 1 membrane glycoprotein, Thy 1 T cell antigen, Thy 1.2, Thy-1 antigen, Thy-1 membrane glycoprotein, Thy1, Thy1 antigen, Thy1 T cell antigen, Thy1.1, Thy1.2, THY1_HUMAN, Thymus cell antigen 1, theta |
| Host | Virus |
| Molecular Weight |
43.3kDa (391aa) 40-57kDa (SDS-PAGE under reducing conditions) |
| Amino Acid Sequence | QKVTSLTACL VDQSLRLDCR HENTSSSPIQ YEFSLTRETK KHVLFGTVGV PEHTYRSRTN FTSKYNMKVL YLSAFTSKDE GTYTCALHHS GHSPPISSQN VTVLRDKLVK CHHHHHH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.25mg/ml (determined by Absorbance at 280nm) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Li Q., et al. (2015) PLoS Pathog. 11:E1004999. Woeller CF., et al. (2015) FASEB J. 29:920-931. |
| Background | THY1, as known as Thy-1 membrane glycoprotein, is a cell membrane protein which contains 1lg-like V-type (immunoglobulin-like) domain. This protein is a member of the immunoglobulin superfamily of adhesion molecules with constitutive expression on fibroblast cells. It can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Also, this protein led to some of the initial biochemical description and characterization of a vertebrate glycophosphatidylinositol (GPI) anchor and also the first demonstration of tissue specific differential glycosylation. Recombinant human THY1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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