| Product Name | TIMM44 Monoclonal Antibody |
|---|---|
| Description | This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma. TIMM44 (Translocase Of Inner Mitochondrial Membrane 44) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Mitochondrial protein import. GO annotations related to this gene include chaperone binding and P-P-bond-hydrolysis-driven protein transmembrane transporter activity. |
| Synonyms | DKFZp686H05241,MIMT44,TIM44,TIMM44 |
| Host | Mouse |
| Clone | 116 |
| Immunogen | Fusion protein of TIMM44 |
| Isotype | IgG2c |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | O43615 |
| Background | This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma. TIMM44 (Translocase Of Inner Mitochondrial Membrane 44) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Mitochondrial protein import. GO annotations related to this gene include chaperone binding and P-P-bond-hydrolysis-driven protein transmembrane transporter activity. |
| Supplier | Elabscience |
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