Product Name | TMPRSS11F Antibody |
---|---|
Description | Rabbit polyclonal antibody to TMPRSS11F |
Synonyms | TMPRSS11F antibody; HATL4 antibody; Transmembrane protease serine 11F antibody; EC 3.4.21.- antibody; Airway trypsin-like protease 4 antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Synthetic peptide of human TMPRSS11F |
Isotype | IgG |
Target | TMPRSS11F |
Reactivity | Human, Mouse |
Applications | ELISA, IHC, WB |
Form | Liquid |
Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Uniprot | Q6ZWK6 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain. |
Supplier | Cusabio |
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