| Product Name | TNFSF13, 105-247aa Human, T7-tagged |
|---|---|
| Description | TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. TNFSF13 and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Recombinant human TNFSF13 protein, fused to T7-tag at N-terminus, was expressed in E.coli. |
| Synonyms | tumor necrosis factor (ligand) superfamily, member 13, APRIL, CD256, TALL2, TRDL-1, ligand, UNQ383/PRO715 |
| Host | E.coli |
| Molecular Weight | 39.0 kDa(352aa) |
| Amino Acid Sequence | MASMTGGQQM GRGSHMAVLT QKQKKQHSVL HLVPINATSK DDSDVTEVMW QPALRRGRGL QAQGYGVRIQ DAGVYLLYSQ VLFQDVTFTM GQVVSREGQG RQETLFRCIR SMPSHPDRAY NSCYSAGVFH LHQGDILSVI IPRARAKLNL SPHGTFLGL |
| Tag | T7 tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea |
| Concentration | 0.5mg/ml (determined by Bradford assay) |
| Purity | > 85% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
| References |
Pollard,R.P, et al. (2013) Ann. Rheum. Dis. 72 (1), 146-148 Notas,G., et al. (2012) J. Immunol. 189 (10), 4748-4758 |
| Supplier | ARP |
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