Tumor necrosis factor receptor superfamily member 8, 19-379aa, Human, Baculovirus
| Product Name | Tumor necrosis factor receptor superfamily member 8, 19-379aa, Human, Baculovirus |
|---|---|
| Description | TNFRSF8, also known as Tumor necrosis factor receptor superfamily member 8, is receptor for TNFSF8/CD30L. It may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Also, this protein regulates gene expression through activation of NF-kappa-B. As a regulator of apoptosis, TNFRSF8 induces cell death or proliferation, depending on the cell type. Recombinant human TNFRSF8, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | TNFRSF8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30 |
| Host | Virus |
| Molecular Weight |
39.4kDa (359aa) 40-57KDa (SDS-PAGE under reducing conditions.) |
| Amino Acid Sequence | ADPFPQDRPF EDTCHGNPSH YYDKAVRRCC YRCPMGLFPT QQCPQRPTDC RKQCEPDYYL DEADRCTACV TCSRDDLVEK TPCAWNSSRV CECRPGMFCS TSAVNSCARC FFHSVCPAGM IVKFPGTAQK NTVCEPASPG VSPACASPEN CKEPSSGTIP QAKPTPVSPA TSSASTMPVR GGTRLAQEAA SKLTRAPDSP SSVGRPSSDP GLSPTQPCPE GSGDCRKQCE PDYYLDEAGR CTACVSCSRD DLVEKTPCAW NSSRTCECRP GMICATSATN SCARCVPYPI CAAETVTKPQ DMAEKDTTFE APPLGTQPDC NPTPENGEAP ASTSPTQSLL VDSQASKTLP IPTSAPVALS STGKHHHHHH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM MES (pH5.5) containing 1mM DTT, 1mM PMSF, 30% glycerol. |
| Concentration | 1.0mg/ml (determined by Absorbance at 280nm) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Yao J., et al. (2013) Am. J. Surg. Pathol. 37(9):1407-1412. Velasquez SY., et al. (2013) Transplantation 96(2):154-161. |
| Background | TNFRSF8, also known as Tumor necrosis factor receptor superfamily member 8, is receptor for TNFSF8/CD30L. It may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Also, this protein regulates gene expression through activation of NF-kappa-B. As a regulator of apoptosis, TNFRSF8 induces cell death or proliferation, depending on the cell type. Recombinant human TNFRSF8, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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