| Product Name | UBD, 1-165aa, Human |
|---|---|
| Description | UBD, also known as Ubiquitin D, is an ubiquitin-like modifier (UBL) of the ubiquitin protein family. UBD is an ubiquitin-like protein that can form covalent conjugates, thereby targeting proteins for degradation by the 26S proteasome. UBD has putative roles in regulation of cell cycle, innate immunity, and apoptosis. UBD is a TNF-alpha-inducible ubiquitin-like protein with a putative role in immune response. Recombinant human UBD protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Synonyms | Ubiquitin D, Diubiquitin, FAT10, GABBR1, UBD-3 |
| Host | E. coli |
| Molecular Weight | 21.6 kDa (196aa), confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAPNASC LCVHVRSEEW DLMTFDANPY DSVKKIKEHV RSKTKVPVQD QVLLLGSKIL KPRRSLSSYG IDKEKTIHLT LKVVKPSDEE LPLFLVESGD EAKRHLLQVR RSSSVAQVKA MIETKTGIIP ETQIVTCNGK RLEDGKMMAD YGIRKGNLLF LACYCIGG |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl. |
| Concentration | 1 mg/ml (determined by Bradford assay ) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Hipp M.S., et al. (2005) Mol. Cell. Biol. 25:3483-3491 Ross M.J., et al. (2006) J. Am. Soc. Nephrol. 17:996-1004 |
| Background | UBD, also known as Ubiquitin D, is an ubiquitin-like modifier (UBL) of the ubiquitin protein family. UBD is an ubiquitin-like protein that can form covalent conjugates, thereby targeting proteins for degradation by the 26S proteasome. UBD has putative roles in regulation of cell cycle, innate immunity, and apoptosis. UBD is a TNF-alpha-inducible ubiquitin-like protein with a putative role in immune response. Recombinant human UBD protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Supplier | ARP |
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