| Product Name | UBE2G2, 1-165aa, Human |
|---|---|
| Description | UBE2G2 also known as Ubiquitin-conjugating enzyme E2 G2 isoform 1. The modification of UBE2G2 with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. UBE2G2 is ubiquitously expressed, with high expression seen in adult muscle. Recombinant human UBE2G2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | Ubiquitin-conjugating enzyme E2 G2 isoform 1, UBC7 |
| Host | E. coli |
| Molecular Weight | 58.4kDa (513aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAGTALK RLMAEYKQLT LNPPEGIVAG PMNEENFFEW EALIMGPEDT CFEFGVFPAI LSFPLDYPLS PPKMRFTCEM FHPNIYPDGR VCISILHAPG DDPMGYESSA ERWSPVQSVE KILLSVVSML AEPNDESGAN VDASKMWRDD REQFYKIAKQ IVQKSLGL |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate buffered saline (pH7.4) containing 20% glycerol, 1mM DTT |
| Concentration | 1mg/ml (determined by Absorbance at 280nm) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Liu W., et al. (2014) EMBO J. 33 (1), 46-61 Spandl J., et al. (2011) J. Biol. Chem. 286 (7), 5599-5606 |
| Background | UBE2G2 also known as Ubiquitin-conjugating enzyme E2 G2 isoform 1. The modification of UBE2G2 with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. UBE2G2 is ubiquitously expressed, with high expression seen in adult muscle. Recombinant human UBE2G2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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