| Product Name | Ubiquitin Human, Recombinant |
|---|---|
| Description | Ubiquitin is a small protein that is composed of 76 amino acids and its sequence is highly conserved throughout evolution from invertebrates to mammals. In the cytoplasm, ubiquitin is involved in ATP-dependent nonlysomal proteolysis of various proteins. In the nucleus, ubiquitin is conjugated to histone2A and may play a role in regulation of chromatin structure and/or regulation of transcriptional activity. Ubiquitin(76amino acid) was overexpressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | RPS27A, UBA80, UBCEP1, UBA52, UBCEP2, UBB, UBC, Ubiquitin, FLJ25987, MGC8385, Polyubiquitin B, Ubiquitin B, |
| Host | E. coli |
| Molecular Weight | 28 kDa (245 aa), confirmed by MALDI-TOF. |
| Amino Acid Sequence | MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN IQKESTLHLV LRLRGG |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris 8.0, 0.2mM PMSF, 2mM EDTA |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Lund PK., et al. (1985) J Biol. Chem. 260(12), 7609-7613. Pancre V., et al. (1991) Eur J Immunol. 21(11):2735-41. |
| Background | Ubiquitin is a small protein that is composed of 76 amino acids and its sequence is highly conserved throughout evolution from invertebrates to mammals. In the cytoplasm, ubiquitin is involved in ATP-dependent nonlysomal proteolysis of various proteins. In the nucleus, ubiquitin is conjugated to histone2A and may play a role in regulation of chromatin structure and/or regulation of transcriptional activity. Ubiquitin(76amino acid) was overexpressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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