| Product Name | UFM1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to UFM1 |
| Synonyms | BM 002 antibody; BM002 antibody; C13orf20 antibody; Chromosome 13 open reading frame 20 antibody; Ubiquitin fold modifier 1 antibody; Ubiquitin-fold modifier 1 antibody; UFM1 antibody; UFM1_HUMAN antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Ubiquitin-fold modifier 1 protein (11-63AA) |
| Isotype | IgG |
| Target | UFM1 |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Uniprot | P61960 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847). This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes. TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (PubMed:25219498). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress (Probable). |
| Supplier | Cusabio |
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