| Product Name | ULBP2, 26-216aa, Human, Baculovirus |
|---|---|
| Description | ULBP2, also known as NKG2D ligand 2, is a member of a family of cell-surface proteins that function as ligands for human NKG2D. It could activate NKT cells and might indicate a mechanism by which clarithromycin improves the clearance of P. aeruginosa in chronic respiratory diseases. It is a useful serum biomarker for pancreatic cancer detection. Recombinant human ULBP2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | NKG2D ligand 2, ULBP2, ALCAN-alpha, N2DL2, NKG2DL2, RAET1H |
| Host | Virus |
| Molecular Weight |
61.3kDa (545aa) 50-70kDa (SDS-PAGE under reducing conditions.) |
| Amino Acid Sequence | ADPGRADPHS LCYDITVIPK FRPGPRWCAV QGQVDEKTFL HYDCGNKTVT PVSPLGKKLN VTTAWKAQNP VLREVVDILT EQLRDIQLEN YTPKEPLTLQ ARMSCEQKAE GHSSGSWQFS FDGQIFLLFD SEKRMWTTVH PGARKMKEKW ENDKVVAMSF HYFSMGDCIG WLEDFLMGMD STLEPSAGAP LAMSHHHHHH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 50mM MES buffer (pH 5.5) containing 40% glycerol, 5mM CaCl2, 1mM DTT, 0.5M NaCl. |
| Concentration | 0.25mg/ml (determined by Absorbance at 280nm) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Okada K., et al. (2015) Yonago Acta Med. 58:31-38. Chang YT., et al. (2011) PLoS One. 6:e20029. |
| Background | ULBP2, also known as NKG2D ligand 2, is a member of a family of cell-surface proteins that function as ligands for human NKG2D. It could activate NKT cells and might indicate a mechanism by which clarithromycin improves the clearance of P. aeruginosa in chronic respiratory diseases. It is a useful serum biomarker for pancreatic cancer detection. Recombinant human ULBP2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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