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|Product Name||VBP1, 1-197aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMAAVKDS CGKGEMATGN GRRLHLGIPE AVFVEDVDSF MKQPGNETAD TVLKKLDEQY QKYKFMELNL AQKKRRLKGQ IPEIKQTLEI LKYMQKKKES TNSMETRFLL ADNLYCKASV PPTDKVCLWL GANVMLEYDI DEAQALLEKN LSTATKNLDS LEEDLDFLRD QFTTTEVNMA RVYNWDVKRR NKDDSTKNKA|
|Background||Prefoldin subunit 3, also known as VBP1, belongs to the prefoldin subunit alpha family. VBP1 interacts with the Von Hippel-Lindau protein to form an intracellular complex. Because it functions as a chaperone protein, it is suspected that it may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Recombinant human VBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||0.25 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.5) containing 0.2M NaCl, 30% glycerol, 1mM DTT|
|Intended Use||For Research Use Only|
|Molecular Weight||17 kDa (165aa), confirmed by MALDI-TOF|
|NCBI Accession #||NP_003363|
|Purity||> 90% by SDS-PAGE|
|References||Kim S Y., et al. (2008) BMB Rep. 41(2):158-63.
Mousnier A., et al. (2007) Proc Natl Acad Sci USA. 201(34):13612-20.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Prefoldin subunit 3, PFD3, PFDN3, VBP-1|
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