| Product Name | Villin Monoclonal Antibody |
|---|---|
| Description | Villin 1 (VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border,like epithelial cells of the intestinal mucosa,gall bladder,renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein,and to have an important function in regulating actin dynamics,cell morphology,epithelial-to-mesenchymal transitions,cell migration and cell survival. In addition,VIL1 is a useful diagnostic marker for of various cancer,like cervical and endometrial adenocarcinomas,renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC. |
| Synonyms | VIL,VIL1,Villin,villin 1 |
| Host | Mouse |
| Clone | 12C |
| Immunogen | Fusion protein of Villin |
| Isotype | IgG1 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P09327 |
| Background | Villin 1 (VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border,like epithelial cells of the intestinal mucosa,gall bladder,renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein,and to have an important function in regulating actin dynamics,cell morphology,epithelial-to-mesenchymal transitions,cell migration and cell survival. In addition,VIL1 is a useful diagnostic marker for of various cancer,like cervical and endometrial adenocarcinomas,renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC. |
| Supplier | Elabscience |
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