| Product Name | YY1 Monoclonal Antibody |
|---|---|
| Description | YY1,also named as DELTA,INO80S and NF-E1,contains four C2H2-type zinc fingers and belongs to the YY transcription factor family. YY1 is a multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter,thus implicating histone modification in the YY1. The open reading frame of the human YY1 cDNA encodes a protein of 414 amino acids with a predicted molecular weight of 44 kDa. However,YY1 migrates on SDS gels as a 65Ð68 kDa protein,probably due to the structure of the protein. It is a ubiquitously expressed transcription factor with fundamental roles in embryogenesis,differentiation,replication and proliferation. |
| Synonyms | DELTA,Delta transcription factor,INO80 complex subunit S,INO80S,NF E1,UCRBP,Yin and yang 1,YIN YANG 1,YY 1,YY1,YY1 transcription factor |
| Host | Mouse |
| Clone | 364 |
| Immunogen | Fusion protein of YY1 |
| Isotype | IgG2a |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P25490 |
| Background | YY1,also named as DELTA,INO80S and NF-E1,contains four C2H2-type zinc fingers and belongs to the YY transcription factor family. YY1 is a multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter,thus implicating histone modification in the YY1. The open reading frame of the human YY1 cDNA encodes a protein of 414 amino acids with a predicted molecular weight of 44 kDa. However,YY1 migrates on SDS gels as a 65Ð68 kDa protein,probably due to the structure of the protein. It is a ubiquitously expressed transcription factor with fundamental roles in embryogenesis,differentiation,replication and proliferation. |
| Supplier | Elabscience |
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