| Product Name | Z-Phe-CMK |
|---|---|
| Description | Z-Phe-CMK, also known as SL-01 and ZPCK, is a chymotrypsin inhibitor. Z-Phe-CMK has been shown to inhibit both peptidase and esterase activities of carboxypeptidase Y from baker's yeast. |
| Synonyms | SL-01, ZPCK, |
| Molecular Weight | 331.8 Da |
| Target | Serine proteases |
| Amino Acid Sequence | N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-carbamic acid-phenylmethyl ester |
| Form | White solid |
| Purity | >95% by tlc |
| Cas Number | 26049-94-5 |
| Storage | Store dry, frozen and in the dark |
| References |
Segal et al (1971) Substrate binding site in bovine chymotrypsin A-gamma. A crystallographic study using peptide chloromethyl ketones as site-specific inhibitors. Biochemistry 10(20) 3728 PMID: 5107010Hayashi et al (1975) Evidence for an essential histidine in carboxypeptidase Y. Reaction with the chloromethyl ketone derivative of benzyloxycarbonyl-L-phenylalanine. J. Biol. Chem. 250(13) 5221 PMID: 238980 Volbracht et al (2001) Apoptosis in caspase-inhibited neurons. Mol. Med. 7(1) 36 PMID: 11474126 Related areasAll small molecules >All serine protease modulators > |
| Supplier | Isca Biochemicals Limited |
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